Light microscopy is a cornerstone in life sciences technology, having experienced considerable diversification since its inception. This development becomes visible when considering the distinctive ...

Light-sheet fluorescence microscopy (LSFM), with its innovative design of selective plane illumination and orthogonal detection optics, significantly reduces phototoxicity and photobleaching inherent ...

The brain is the most energy-demanding organ in the body, in part due to its complexity. Its components are varied and intricate: comprising different cell types, including neurons designed to ...

Light microscopy is one of the most essential technologies in life science research. Advances in optoelectronic detectors and the widespread availability of laser-based light sources have led to the ...

SLICE addresses one of the most significant challenges in modern biological research: the limited accessibility of high-performance light sheet microscopy due to high costs and complex infrastructure ...

Light-sheet microscopy is a rapidly developing field thanks to the numerous benefits and vast number of implementations when imaging with a light sheet. However, these benefits are best realized when ...

Analyzing the response of cells to heat shock is an established way to study the behavior of cells in changing conditions, and understand their natural survival mechanisms. A project at the University ...

Researchers have incorporated a swept illumination source into an open-top light-sheet microscope to enable improved optical sectioning over a larger area of view. The advance makes the technique more ...

Image of an open-top light-sheet microscope. Credit: Kevin W. Bishop, University of Washington Researchers have incorporated a swept illumination source into an open-top light-sheet microscope to ...